Overcoming Cancer with Research - Making Successes Public

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Development of new Therapeutic Approaches

Last update on: 04/09/2009


Despite preventive measures, many children suffering from cancer contract life-threatening fungal infections during a period of reduced resistance, e.g. during the course of intensive chemotherapy or an allogenic stem cell transplant.

While invasive fungal infections don't play a roll for healthy persons, they represent a serious complication for cancer patients. The most frequent of the fungi is the genus Aspergillus.


To respond to this, now a completed project, an immunotherapeutic approach to the treatment of Aspergillum infections was developed. The project was funded with a total of 462,452 Euros (DLFH 2005.02 and 2003.01).


"Development of an immunotherapy with Aspergillus-specific allogenic T cells for children following a stem cell transplant"

Prof. Dr. Thomas Lehrnbecher,

Centre for Paediatric Cancer Research at the University Frankfurt a. Main